Bcr (phospho Tyr360) antibody

GeneTex

Bcr (phospho Tyr360) antibody

10

Western Blot

Research Use Only

Polyclonal

1 mg/ml

Rabbit

IgG

Phosphorylated

A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Human, Monkey

2°C to 8°C,-20°C

12352203