GTX635160 ELISA Image
beta Amyloid (1-42) antibody - Conformation Specific antibody [GT622]
GTX635160
Product group Antibodies
Overview
- SupplierGeneTex
- Product Namebeta Amyloid (1-42) antibody - Conformation Specific antibody [GT622]
- Delivery Days Customer9
- CertificationResearch Use Only
- Clone IDGT622
- Concentration0.27 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Improved modeling of human AD with an automated culturing platform for iPSC neurons, astrocytes and microglia. Bassil R et al., 2021 Sep 1, Nat CommunRead more