GTX101254 WB Image
GTX101254 WB Image
beta Catenin antibody
GTX101254
Product group Antibodies
Overview
- SupplierGeneTex
- Product Namebeta Catenin antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1.01 mg/ml
- IsotypeIgG
- Scientific DescriptionBeta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. AJs may also function in the transmission of the contact inhibition signal, which instructs cells to stop dividing once an epithelial sheet is complete.[supplied by OMIM]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Arsenic exposure inhibits myogenesis and neurogenesis in P19 stem cells through repression of the beta-catenin signaling pathway. Hong GM et al., 2012 Sep, Toxicol SciRead more
- LncRNA TTN-AS1/miR-134-5p/PAK3 axis regulates the radiosensitivity of human large intestine cancer cells through the P21 pathway and AKT/GSK-3beta/beta-catenin pathway. Zuo Z et al., 2020 Nov, Cell Biol IntRead more
- LncRNA TTN-AS1/miR-134-5p/PAK3 axis regulates the radiosensitivity of human large intestine cancer cells through the P21 pathway and AKT/GSK-3beta/beta-catenin pathway. Zuo Z et al., 2020 Nov, Cell Biol IntRead more
- Macrophages mediate a switch between canonical and non-canonical Wnt pathways in canine mammary tumors. Krol M et al., 2014, PLoS OneRead more
- miR-338-3p inhibits A549 lung cancer cell proliferation and invasion by targeting AKT and beta-catenin signaling pathways. Liu J et al., 2019 Jul, Mol Med RepRead more
- MiRNA-21 induces epithelial to mesenchymal transition and gemcitabine resistance via the PTEN/AKT pathway in breast cancer. Wu ZH et al., 2016 Jun, Tumour BiolRead more
- Starvation beneficially influences the liver physiology and nutrient metabolism in Edwardsiella tarda infected red sea bream (Pagrus major). Mohapatra S et al., 2015 Nov, Comp Biochem Physiol A Mol Integr PhysiolRead more