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GTX100874 ICC/IF Image
GTX100874 ICC/IF Image
GTX100874 ICC/IF Image

BMP4 antibody

Research Use Only
GTX100874
GeneTex
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    BMP4 antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.36 mg/ml
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5 untranslated region of this gene has been described and three variants are described, all encoding an identical protein. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Bone morphogenetic protein 4 (BMP4) alleviates hepatic steatosis by increasing hepatic lipid turnover and inhibiting the mTORC1 signaling axis in hepatocytes. Peng Q et al., 2019 Dec 12, Aging (Albany NY)
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  • Decrease of FSTL1-BMP4-Smad signaling predicts poor prognosis in lung adenocarcinoma but not in squamous cell carcinoma. Chiou J et al., 2017 Aug 29, Sci Rep
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  • TSA restores hair follicle-inductive capacity of skin-derived precursors. Guo L et al., 2019 Feb 27, Sci Rep
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