Bio-Connect

BRCA1 antibody

Research Use Only
ORB48292
Biorbyt
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biorbyt
  • Product Name
    BRCA1 antibody
  • Delivery Days Customer
    16
  • Applications Supplier
    WB: 1:500-2000, IHC-P: 1:50-200, IF/ICC: 1:20-50 ICC, IF, IHC-P, WB
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Isotype
    IgG
  • Scientific Description
    Rabbit polyclonal antibody to BRCA1 also known as RING finger protein 53 whose expression can be detected in cancer but is highly expressive in several breast and ovarian cancer cell lines. It is found in the nucleus. BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. It also regulates centrosomal microtubule nucleation required for normal cell cycle progression from G2 to mitosis and appropriate cell cycle arrests after ionizing irradiation in both the S-phase and the G2 phase of the cell cycle.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203