Cadherin 16 Antibody
ORB386237
Overview
- SupplierBiorbyt
- Product NameCadherin 16 Antibody
- Delivery Days Customer16
- ApplicationsFlow Cytometry
- Applications SupplierWestern blot: 1-2ug/ml,Flow cytometry: 1-2ug/million cells,Immunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT FACS, IHC-P, WB
- CertificationResearch Use Only
- Clone IDCDH16/1532R
- IsotypeIgG
- Scientific DescriptionCadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that CDH16 (kidney-specific cadherin, Cadherin 16) is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, CDH16 is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. CDH16 has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
- UNSPSC12352203