Bio-Connect

CARD14 antibody

Research Use Only
GTX82208
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    CARD14 antibody
  • Delivery Days Customer
    10
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Host
    Chicken
  • Isotype
    IgY
  • Scientific Description
    Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10. The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family. a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family. which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein shares a similar domain structure with CARD11 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10. a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells. this protein activated NF-kappaB and induced the phosphorylation of BCL10. Two alternatively spliced variants of this gene encoding distinct isoforms have been reported.
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203