CARD14 antibody
GTX82208
Overview
- SupplierGeneTex
- Product NameCARD14 antibody
- Delivery Days Customer10
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- HostChicken
- IsotypeIgY
- Scientific DescriptionActivates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10. The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family. a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family. which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein shares a similar domain structure with CARD11 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10. a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells. this protein activated NF-kappaB and induced the phosphorylation of BCL10. Two alternatively spliced variants of this gene encoding distinct isoforms have been reported.
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203