Cardiac Troponin C antibody [1A2]
GTX28285
ApplicationsWestern Blot, ELISA, Purification/Extraction/Isolation
Product group Antibodies
ReactivityHuman
Overview
- SupplierGeneTex
- Product NameCardiac Troponin C antibody [1A2]
- Delivery Days Customer10
- ApplicationsWestern Blot, ELISA, Purification/Extraction/Isolation
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID1A2
- HostMouse
- IsotypeIgG
- Scientific DescriptionTroponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203