Cardiac Troponin I antibody [19C7]
GTX28289
ApplicationsImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry, Other Application, Purification/Extraction/Isolation
Product group Antibodies
ReactivityBovine, Canine, Feline, Fish, Goat, Human, Mouse, Porcine, Rabbit, Rat
Overview
- SupplierGeneTex
- Product NameCardiac Troponin I antibody [19C7]
- Delivery Days Customer10
- ApplicationsImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry, Other Application, Purification/Extraction/Isolation
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID19C7
- HostMouse
- IsotypeIgG
- Scientific DescriptionTroponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]
- ReactivityBovine, Canine, Feline, Fish, Goat, Human, Mouse, Porcine, Rabbit, Rat
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
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- Copy number variant hotspots in Han Taiwanese population induced pluripotent stem cell lines - lessons from establishing the Taiwan human disease iPSC Consortium Bank. Huang CY et al., 2020 Sep 4, J Biomed SciRead more
- Copy number variant hotspots in Han Taiwanese population induced pluripotent stem cell lines - lessons from establishing the Taiwan human disease iPSC Consortium Bank. Huang CY et al., 2020 Sep 4, J Biomed SciRead more
- Heart failure-inducible gene therapy targeting protein phosphatase 1 prevents progressive left ventricular remodeling. Miyazaki Y et al., 2012, PLoS OneRead more
- Isoform-specific roles of protein phosphatase 1 catalytic subunits in sarcoplasmic reticulum-mediated Ca(2+) cycling. Aoyama H et al., 2011 Jan 1, Cardiovasc ResRead more