Overview
- SupplierGeneTex
- Product NameCatalase antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.47 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimers disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Sanghuangporus sanghuang Mycelium Prevents Paracetamol-Induced Hepatotoxicity through Regulating the MAPK/NF-kappaB, Keap1/Nrf2/HO-1, TLR4/PI3K/Akt, and CaMKKbeta/LKB1/AMPK Pathways and Suppressing Oxidative Stress and Inflammation. Jiang WP et al., 2021 Jun 2, Antioxidants (Basel)Read more
- 1,25-Dihydroxyvitamin D3 modulates the effects of sublethal BPA on mitochondrial function via activating PI3K-Akt pathway and 17beta-estradiol secretion in rat granulosa cells. Lee CT et al., 2019 Jan, J Steroid Biochem Mol BiolRead more
- 3, 4-dihydroxybenzalacetone attenuates lipopolysaccharide-induced inflammation in acute lung injury via down-regulation of MMP-2 and MMP-9 activities through suppressing ROS-mediated MAPK and PI3K/AKT signaling pathways. Chao W et al., 2017 Sep, Int ImmunopharmacolRead more
- 3,4-Dihydroxybenzalactone Suppresses Human Non-Small Cell Lung Carcinoma Cells Metastasis via Suppression of Epithelial to Mesenchymal Transition, ROS-Mediated PI3K/AKT/MAPK/MMP and NFkappaB Signaling Pathways. Chao W et al., 2017 Mar 28, MoleculesRead more
- A Ketogenic Diet in Rodents Elicits Improved Mitochondrial Adaptations in Response to Resistance Exercise Training Compared to an Isocaloric Western Diet. Hyatt HW et al., 2016, Front PhysiolRead more
- A mitohormetic response to pro-oxidant exposure in the house mouse. Zhang Y et al., 2018 Jan 1, Am J Physiol Regul Integr Comp PhysiolRead more
- Attenuation of Lipopolysaccharide-Induced Acute Lung Injury by Hispolon in Mice, Through Regulating the TLR4/PI3K/Akt/mTOR and Keap1/Nrf2/HO-1 Pathways, and Suppressing Oxidative Stress-Mediated ER Stress-Induced Apoptosis and Autophagy. Huang CY et al., 2020 Jun 10, NutrientsRead more
- Bovine Milk Extracellular Vesicles (EVs) Modification Elicits Skeletal Muscle Growth in Rats. Parry HA et al., 2019, Front PhysiolRead more
- Caffeic acid and resveratrol ameliorate cellular damage in cell and Drosophila models of spinocerebellar ataxia type 3 through upregulation of Nrf2 pathway. Wu YL et al., 2018 Feb 1, Free Radic Biol MedRead more
- Catalase Mediates the Inhibitory Actions of PPARdelta against Angiotensin II-Triggered Hypertrophy in H9c2 Cardiomyocytes. Hwang JS et al., 2021 Jul 29, Antioxidants (Basel)Read more