Cathepsin L antibody, MAb

Biorbyt

Cathepsin L antibody, MAb

10

Western Blot, ImmunoHistoChemistry

Western blot - 2 μg/ml - Human, mouse, rat - - - Immunohistochemistry(Frozen Section) - 4 μg/ml - Human, mouse, rat - - - WB, IHC

Research Use Only

Monoclonal

Clone: 33/2

100 ug/ml

Mouse

IgG1

Mouse monoclonal antibody to Cathepsin L is a lysosomal cysteine proteinase with a major role in intracellular protein catabolism. It also shows the most potent collagenolytic and elastinolytic activity in vitro of any of the cathepsins. Cathepsin L has been implicated in pathologic processes including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. Human liver cathepsin L consists of a heavy chain of about 25 kD and a light chain of about 5 kD. The gene is mapped to 9q21-q22. Cathepsin L is required for endothelial progenitor cell-induced neovascularization.

Human, Mouse, Rat

2°C to 8°C,-20°C

12352203