CD11a antibody [WT.1] (Biotin)

GeneTex

CD11a antibody [WT.1] (Biotin)

10

Flow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, Neutralisation/Blocking

Research Use Only

Monoclonal

WT.1

0.1 mg/ml

Mouse

IgG

ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Rat

2°C to 8°C,-20°C

12352203