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GTX100567 WB Image
GTX100567 WB Image
GTX100567 WB Image

CD133 antibody [C1C2], Internal

Research Use Only
GTX100567
GeneTex
Product group Antibodies
Price on request
Packing Size
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Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    CD133 antibody [C1C2], Internal
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    1.00 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Dual drug-loaded biofunctionalized amphiphilic chitosan nanoparticles: Enhanced synergy between cisplatin and demethoxycurcumin against multidrug-resistant stem-like lung cancer cells. Huang WT et al., 2016 Dec, Eur J Pharm Biopharm
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  • Establishment of an Immunocompetent Metastasis Rat Model with Hepatocyte Cancer Stem Cells. Wu S et al., 2020 Dec 11, Cancers (Basel)
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  • Identification and Characterization of CD133(pos) Subpopulation Cells From a Human Laryngeal Cancer Cell Line. Qiu HO et al., 2016 Apr 6, Med Sci Monit
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  • Onconase Restores Cytotoxicity in Dabrafenib-Resistant A375 Human Melanoma Cells and Affects Cell Migration, Invasion and Colony Formation Capability. Raineri A et al., 2019 Nov 27, Int J Mol Sci
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  • p21-Activated kinase 3 promotes cancer stem cell phenotypes through activating the Akt-GSK3beta-beta-catenin signaling pathway in pancreatic cancer cells. Wu HY et al., 2019 Aug 1, Cancer Lett
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  • PCDH10 exerts tumor-suppressor functions through modulation of EGFR/AKT axis in colorectal cancer. Jao TM et al., 2021 Feb 28, Cancer Lett
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  • Suppression of cancer stemness by upregulating Ligand-of-Numb protein X1 in colorectal carcinoma. Ma L et al., 2017, PLoS One
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