Overview
- SupplierGeneTex
- Product NameCD133 antibody [C1C2], Internal
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1.00 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Dual drug-loaded biofunctionalized amphiphilic chitosan nanoparticles: Enhanced synergy between cisplatin and demethoxycurcumin against multidrug-resistant stem-like lung cancer cells. Huang WT et al., 2016 Dec, Eur J Pharm BiopharmRead more
- Establishment of an Immunocompetent Metastasis Rat Model with Hepatocyte Cancer Stem Cells. Wu S et al., 2020 Dec 11, Cancers (Basel)Read more
- Identification and Characterization of CD133(pos) Subpopulation Cells From a Human Laryngeal Cancer Cell Line. Qiu HO et al., 2016 Apr 6, Med Sci MonitRead more
- Onconase Restores Cytotoxicity in Dabrafenib-Resistant A375 Human Melanoma Cells and Affects Cell Migration, Invasion and Colony Formation Capability. Raineri A et al., 2019 Nov 27, Int J Mol SciRead more
- p21-Activated kinase 3 promotes cancer stem cell phenotypes through activating the Akt-GSK3beta-beta-catenin signaling pathway in pancreatic cancer cells. Wu HY et al., 2019 Aug 1, Cancer LettRead more
- PCDH10 exerts tumor-suppressor functions through modulation of EGFR/AKT axis in colorectal cancer. Jao TM et al., 2021 Feb 28, Cancer LettRead more
- Suppression of cancer stemness by upregulating Ligand-of-Numb protein X1 in colorectal carcinoma. Ma L et al., 2017, PLoS OneRead more