Thrombomodulin Antibody / CD141
ORB386063
Overview
- SupplierBiorbyt
- Product NameThrombomodulin Antibody / CD141
- Delivery Days Customer16
- ApplicationsELISA
- Applications SupplierELISA: 2-4ug/ml (order BSA/azide-free format),Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT ELISA, IHC-P
- CertificationResearch Use Only
- Clone IDTHBD/1782
- IsotypeIgG
- Scientific DescriptionIt recognizes a protein of 75kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi s sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.
- UNSPSC12352203