GTX42371 FACS Image
CD160 antibody [BY55] (Azide free)
GTX42371
ApplicationsFlow Cytometry, ImmunoPrecipitation
Product group Antibodies
ReactivityHuman
Overview
- SupplierGeneTex
- Product NameCD160 antibody [BY55] (Azide free)
- Delivery Days Customer10
- ApplicationsFlow Cytometry, ImmunoPrecipitation
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDBY55
- Concentration1 mg/ml
- HostMouse
- IsotypeIgM
- Scientific DescriptionCD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203