CD160 antibody

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Product specifications for - CD160 antibody

Overview:
Product group:	Antibodies
Category:	Primary Antibodies
Application:	ELISA; ImmunoCytoChemistry; ImmunoFluorescence; Western Blot
Species:	Human, Mouse
Host:	Rabbit
Target:	CD160
Target description:	CD160 molecule
Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Controle:	K562 Cell Lysate(GTX27911)

Properties:
Datasheet:	Datasheet
	Research Use Only
UNSPSC:	12352203
Concentration:	1 mg/ml
Storage instructions:	2-¦C to 8-¦C, -20-¦C or -80-¦C

Scientific information:
Scientific info:	CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MH
Gene ID:	11126
Swiss prot ID:	O95971

Additional information:
Synonyms:	BY55; CD160 antigen; CD160 transmembrane isoform; CD160-delta Ig; natural killer cell receptor BY55; natural killer cell receptor, immunoglobulin superfamily member; NK1; NK28

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Product specifications for - CD160 antibody