Bio-Connect

CD19 Antibody / B-lymphocyte marker

Research Use Only
ORB385675
Biorbyt
ApplicationsELISA
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biorbyt
  • Product Name
    CD19 Antibody / B-lymphocyte marker
  • Delivery Days Customer
    16
  • Applications
    ELISA
  • Applications Supplier
    ELISA (order BSA/sodium azide-free format for coating) ELISA
  • Certification
    Research Use Only
  • Clone ID
    C19/366
  • Isotype
    IgG
  • Scientific Description
    CD19 is a transmembrane glycoprotein that contains two extracellular immunoglobulin-like domains. CD19 is present in both benign and malignant B-cells and is considered to be the most reliable surface marker of this lineage over a wide range of maturational stages. In normal lymphoid tissue, CD19 is observed in germinal centers, in mantle zone cells, and in scattered cells of the inter-follicular areas. Anti-CD19 exhibits an overall immunoreactivity pattern similar to those of the antibodies against CD20 and CD22. However, in contrast to CD20, expression of CD19 is continuous throughout B-cell development and through terminal differentiation of B-cells into plasma cells. Anti-CD19 positivity is seen in the vast majority of B-cell neoplasms commonly at a lower intensity than normal B-cell counterparts. Plasma cell neoplasms are nearly always negative, as are T-cell neoplasms.
  • UNSPSC
    12352203