CD27 Antibody
ORB533982
Overview
- SupplierBiorbyt
- Product NameCD27 Antibody
- Delivery Days Customer16
- ApplicationsImmunoHistoChemistry
- Applications SupplierImmunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT,Prediluted IHC only format : incubate for 30 min at RT (1) IHC-P
- CertificationResearch Use Only
- Clone IDCDLA27-1R
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. CD27 transduces signals that lead to the activation of NF-kB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [Wiki]
- UNSPSC12352203