Bio-Connect

CD27 Antibody

Research Use Only
ORB533982
Biorbyt
ApplicationsImmunoHistoChemistry
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biorbyt
  • Product Name
    CD27 Antibody
  • Delivery Days Customer
    16
  • Applications
    ImmunoHistoChemistry
  • Applications Supplier
    Immunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT,Prediluted IHC only format : incubate for 30 min at RT (1) IHC-P
  • Certification
    Research Use Only
  • Clone ID
    CDLA27-1R
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. CD27 transduces signals that lead to the activation of NF-kB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [Wiki]
  • UNSPSC
    12352203