CD34 Antibody
ORB534459
Overview
- SupplierBiorbyt
- Product NameCD34 Antibody
- Delivery Days Customer16
- ApplicationsFlow Cytometry
- Applications SupplierFlow cytometry: 0.5-1ug/million cells,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1) FACS, IHC-P
- CertificationResearch Use Only
- Clone IDCDLA34-2R
- IsotypeIgG
- Scientific DescriptionThis antibody recognizes a transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposis sarcoma, but shows low specificity.
- UNSPSC12352203