Bio-Connect

CD34 Antibody

Research Use Only
ORB534459
Biorbyt
ApplicationsFlow Cytometry
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biorbyt
  • Product Name
    CD34 Antibody
  • Delivery Days Customer
    16
  • Applications
    Flow Cytometry
  • Applications Supplier
    Flow cytometry: 0.5-1ug/million cells,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1) FACS, IHC-P
  • Certification
    Research Use Only
  • Clone ID
    CDLA34-2R
  • Isotype
    IgG
  • Scientific Description
    This antibody recognizes a transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposis sarcoma, but shows low specificity.
  • UNSPSC
    12352203