CD40L / CD154 antibody [5F3]

Catalog number: GTX13546_50ug
Brand: GeneTex
Packing: 50 ug
Price: € 393.00
Expected delivery time: 10 days
GTX13546 FACS Image
GTX13546 FACS Image...

Product specifications for - CD40L / CD154 antibody [5F3]

Product group: Antibodies
Category: Primary Antibodies
Application: Flow Cytometry
Species: Human
Host: Mouse
Target: CD40LG
Target description: CD40 ligand
Clonality: Monoclonal
Conjugation: Unconjugated
Isotype: IgG1
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 1 mg/ml
Storage instructions: 2-¦C to 8-¦C, -20-¦C or -80-¦C
Scientific information: 
Scientific info: CD40 ligand (CD40L), also known as CD154, gp39 and TRAP, is a 33 kDa type II membrane glycoprotein expressed mainly on the cell surface of activated T lymphocytes, but also exists as a soluble form extracellularly. CD40L is the ligand for CD40, a member of the TNF superfamily, which is expressed on the cell surface of B cells, macrophages/monocytes, dendritic cells, vascular endothelial cells, and epithelial cells. CD40L plays an important role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center through interaction with B cells expressing CD40, and activation of CD4+ T cells. Mutation within the CD40L gene is linked to hyper IgM syndrome, an X-linked immunodeficiency disease that is characterized by elevated level of serum IgM and decreased level of other isotypes.
Clone ID: 5F3
Gene ID: 959
Swiss prot ID: P29965
Additional information: 
Synonyms: CD154; CD40 antigen ligand; CD40 ligand; CD40L; CD40-L; gp39; hCD40L; HIGM1; IGM; IMD3; T-B cell-activating molecule; T-BAM; T-cell antigen Gp39; TNF-related activation protein; TNFSF5; TRAP; tumor necrosis factor (ligand) superfamily member 5; Tumor necrosis factor ligand superfamily member 5