CD45RA Antibody (Leukocyte marker)
ORB385828
Overview
- SupplierBiorbyt
- Product NameCD45RA Antibody (Leukocyte marker)
- Delivery Days Customer16
- ApplicationsFlow Cytometry
- Applications SupplierWestern blot: 1-2ug/ml,Flow cytometry: 0.5-1ug/million cells,Immunofluorescence: 1-2 ug/ml,Immunohistology (FFPE): 0.5-1.0ug/ml for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1) FACS, IF, WB, IHC
- CertificationResearch Use Only
- Clone IDCDLA45RA-1
- IsotypeIgG
- Scientific DescriptionCD45RA is an isoform of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. CD45RA is expressed on 40-50% of peripheral CD4+ T-cells, 50% of peripheral CD8+ T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells.
- UNSPSC12352203