Bio-Connect

CD55 antibody (PE)

Research Use Only
ORB12093
Biorbyt
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biorbyt
  • Product Name
    CD55 antibody (PE)
  • Delivery Days Customer
    16
  • Applications Supplier
    FACS, ICC, IF
  • Certification
    Research Use Only
  • Clone ID
    COB55
  • Conjugate
    RPE
  • Isotype
    IgG
  • Scientific Description
    Mouse monoclonal to CD55.COB55 reacts with CD55, a 70 kDa GPI anchored single chain glycoprotein, referred to as decay accelerating factor (DAF). CD55 is widely expressed on hematopoietic cells including erythrocytes and NK cells, as well as on some non-hematopoietic cells. DAF protects cells from damage by autologous complement by preventing the amplification steps of the complement components. A defective PIG-A gene can lead to a deficiency of GPI -liked proteins such as CD55 and an acquired hemolytic anemia. This biological state is called paroxysmal nocturnal hemoglobinuria (PNH). Loss of protective proteins on the cell surface makes the red blood cells of PNH patients sensitive to complement-mediated lysis.
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203