CD55 antibody (PE)
ORB12093
Product group Antibodies
Overview
- SupplierBiorbyt
- Product NameCD55 antibody (PE)
- Delivery Days Customer16
- Applications SupplierFACS, ICC, IF
- CertificationResearch Use Only
- Clone IDCOB55
- ConjugateRPE
- IsotypeIgG
- Scientific DescriptionMouse monoclonal to CD55.COB55 reacts with CD55, a 70 kDa GPI anchored single chain glycoprotein, referred to as decay accelerating factor (DAF). CD55 is widely expressed on hematopoietic cells including erythrocytes and NK cells, as well as on some non-hematopoietic cells. DAF protects cells from damage by autologous complement by preventing the amplification steps of the complement components. A defective PIG-A gene can lead to a deficiency of GPI -liked proteins such as CD55 and an acquired hemolytic anemia. This biological state is called paroxysmal nocturnal hemoglobinuria (PNH). Loss of protective proteins on the cell surface makes the red blood cells of PNH patients sensitive to complement-mediated lysis.
- Storage Instruction2°C to 8°C
- UNSPSC12352203