GTX113170 WB Image
GTX113170 WB Image
CD55 antibody [N1C2]
GTX113170
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameCD55 antibody [N1C2]
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.86 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF); binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Differential Expression of Complement Markers in Normal and AMD Transmitochondrial Cybrids. Nashine S et al., 2016, PLoS OneRead more
- Expression of human decay-accelerating factor on intestinal epithelium of transgenic mice does not facilitate infection by the enteral route. Pan J et al., 2015 Apr, J VirolRead more