GTX108120 IHC-P Image
GTX108120 IHC-P Image
CDC2 antibody [N1], N-term
GTX108120
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameCDC2 antibody [N1], N-term
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Melissa officinalis Extract Induces Apoptosis and Inhibits Migration in Human Colorectal Cancer Cells. Kuo TT et al., 2020 Dec 15, ACS OmegaRead more
- A high-throughput pipeline for validation of antibodies. Sikorski K et al., 2018 Nov, Nat MethodsRead more
- Anti-proliferative and gene expression actions of resveratrol in breast cancer cells in vitro. Chin YT et al., 2014 Dec 30, OncotargetRead more
- Escin induces apoptosis in human renal cancer cells through G2/M arrest and reactive oxygen species-modulated mitochondrial pathways. Yuan SY et al., 2017 Feb, Oncol RepRead more
- Intrahepatic hepatitis B virus large surface antigen induces hepatocyte hyperploidy via failure of cytokinesis. Li TN et al., 2018 Aug, J PatholRead more
- Licochalcone A attenuates glioma cell growth in vitro and in vivo through cell cycle arrest. Lu WJ et al., 2018 Aug 15, Food FunctRead more
- Macrophage Migration Inhibitory Factor Acts as the Potential Target of a Newly Synthesized Compound, 1-(9-methyl-3-carbazole)-3, 4-dihydro-beta-carboline. Ko PH et al., 2019 Feb 14, Sci RepRead more
- Polo-like kinase inhibitor Ro5203280 has potent antitumor activity in nasopharyngeal carcinoma. Cheung AK et al., 2013 Aug, Mol Cancer TherRead more
- Protein kinase A-mediated serine 35 phosphorylation dissociates histone H1.4 from mitotic chromosome. Chu CS et al., 2011 Oct 14, J Biol ChemRead more
- Suppression of cell-cycle progression by Jun dimerization protein-2 (JDP2) involves downregulation of cyclin-A2. Pan J et al., 2010 Nov 25, OncogeneRead more