GTX110586 ICC/IF Image
GTX110586 ICC/IF Image
CDC45L antibody [N3C3]
GTX110586
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameCDC45L antibody [N3C3]
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.73 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple polyadenlyation sites of this gene are reported. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Histone demethylase Kdm4b functions as a co-factor of C/EBPbeta to promote mitotic clonal expansion during differentiation of 3T3-L1 preadipocytes. Guo L et al., 2012 Dec, Cell Death DifferRead more