CDK5 antibody, PAb

Biorbyt

CDK5 antibody, PAb

16

Western Blot

Western blot - 0.1-0.5 μg/ml - Human, Rat - Mouse - WB

Research Use Only

Polyclonal

500 ug/ml

Rabbit

IgG

Rabbit Polyclonal to CDK5. CDK5, Cyclin-Dependent Kinase5,is also know as PSSALRE. The p34(CDC2) protein kinase regulates important transitions in the eukaryotic cell cycle.The PSSALRE expression is in all human tissues and cell lines tested.The the CDK5 gene is mapped to chromosome 7q36. Cyclin-dependent kinase-5 is predominantly expressed in neurons where it phosphorylates both high molecular weight neurofilaments and microtubule-associated protein tau. CDK5 is required for proper development of the mammalian central nervous system . To be activated, CDK5 must associate with its regulatory subunit, p35 (CDK5R1). CDK5 can phosphorylate DARPP32 at threonine-75, converting it into an inhibitor of PKA .

Hamster, Human, Mouse, Rat

2°C to 8°C,-20°C

12352203