Overview
- SupplierGeneTex
- Product NameCDK6 antibody [N1C3]
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.66 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
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- Extracellular vesicles from neurons promote neural induction of stem cells through cyclin D1. Song L et al., 2021 Sep 6, J Cell BiolRead more
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- Licochalcone A attenuates glioma cell growth in vitro and in vivo through cell cycle arrest. Lu WJ et al., 2018 Aug 15, Food FunctRead more
- Prognostic and therapeutic value of disruptor of telomeric silencing-1-like (DOT1L) expression in patients with ovarian cancer. Zhang X et al., 2017 Jan 23, J Hematol OncolRead more
- Proteasome 26S Subunit, non-ATPase 3 (PSMD3) Regulates Breast Cancer by Stabilizing HER2 from Degradation. Fararjeh AS et al., 2019 Apr 12, Cancers (Basel)Read more