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GTX103992 IHC-P Image
GTX103992 IHC-P Image
GTX103992 IHC-P Image

CDK6 antibody [N1C3]

Research Use Only
GTX103992
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    CDK6 antibody [N1C3]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.66 mg/ml
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

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  • Aqueous extracts of Paeonia suffruticosa modulates mitochondrial proteostasis by reactive oxygen species-induced endoplasmic reticulum stress in pancreatic cancer cells. Liu YH et al., 2018 Jul 15, Phytomedicine
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  • Double homeobox gene, Duxbl, promotes myoblast proliferation and abolishes myoblast differentiation by blocking MyoD transactivation. Wu SL et al., 2014 Nov, Cell Tissue Res
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  • Effects and mechanisms of betulinic acid on improving EGFR TKI-resistance of lung cancer cells. Ko JL et al., 2018 Nov, Environ Toxicol
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  • Extracellular vesicles from neurons promote neural induction of stem cells through cyclin D1. Song L et al., 2021 Sep 6, J Cell Biol
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  • Flavopereirine induces cell cycle arrest and apoptosis via the AKT/p38 MAPK/ERK1/2 signaling pathway in human breast cancer cells. Yeh HT et al., 2019 Nov 15, Eur J Pharmacol
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  • Id1 promotes lung cancer cell proliferation and tumor growth through Akt-related pathway. Cheng YJ et al., 2011 Aug 28, Cancer Lett
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  • Licochalcone A attenuates glioma cell growth in vitro and in vivo through cell cycle arrest. Lu WJ et al., 2018 Aug 15, Food Funct
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  • Prognostic and therapeutic value of disruptor of telomeric silencing-1-like (DOT1L) expression in patients with ovarian cancer. Zhang X et al., 2017 Jan 23, J Hematol Oncol
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  • Proteasome 26S Subunit, non-ATPase 3 (PSMD3) Regulates Breast Cancer by Stabilizing HER2 from Degradation. Fararjeh AS et al., 2019 Apr 12, Cancers (Basel)
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