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GTX124186 IP Image
GTX124186 IP Image
GTX124186 IP Image

CHD4 antibody

Research Use Only
GTX124186
GeneTex
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    CHD4 antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Isotype
    IgG
  • Scientific Description
    The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • CHD4 as an important mediator in regulating the malignant behaviors of colorectal cancer. Chang CL et al., 2021, Int J Biol Sci
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  • CHD4-mediated loss of E-cadherin determines metastatic ability in triple-negative breast cancer cells. Luo CW et al., 2018 Feb 1, Exp Cell Res
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  • Identification of CHD4-beta1 integrin axis as a prognostic marker in triple-negative breast cancer using next-generation sequencing and bioinformatics. Ou-Yang F et al., 2019 Dec 1, Life Sci
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  • Over-Expression of CHD4 Is an Independent Biomarker of Poor Prognosis in Patients with Rectal Cancers Receiving Concurrent Chemoradiotherapy. Wang HC et al., 2019 Aug 21, Int J Mol Sci
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  • Senataxin controls meiotic silencing through ATR activation and chromatin remodeling. Yeo AJ et al., 2015, Cell Discov
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  • The NuRD complex-mediated p21 suppression facilitates chemoresistance in BRCA-proficient breast cancer. Hou MF et al., 2017 Oct 15, Exp Cell Res
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