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GTX84685 ICC/IF Image
GTX84685 ICC/IF Image
GTX84685 ICC/IF Image

Chk2 antibody [2F4] - KO/KD, Overexpression Validated

Research Use Only
GTX84685
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityCanine, Human, Monkey, Mouse, Rat
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    Chk2 antibody [2F4] - KO/KD, Overexpression Validated
  • Delivery Days Customer
    10
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    2F4
  • Concentration
    1.2 mg/ml
  • Host
    Mouse
  • Isotype
    IgG
  • Scientific Description
    Regulates cell cycle checkpoints and apoptosis in response to DNA damage, particularly to DNA double-strand breaks. Inhibits CDC25C phosphatase by phosphorylation on Ser-216, preventing the entry into mitosis. May also play a role in meiosis. Regulates the TP53 tumor suppressor through phosphorylation at Thr-18 and Ser-20.
  • Reactivity
    Canine, Human, Monkey, Mouse, Rat
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203