GTX84685 ICC/IF Image
Chk2 antibody [2F4] - KO/KD, Overexpression Validated
GTX84685
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityCanine, Human, Monkey, Mouse, Rat
Overview
- SupplierGeneTex
- Product NameChk2 antibody [2F4] - KO/KD, Overexpression Validated
- Delivery Days Customer10
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID2F4
- Concentration1.2 mg/ml
- HostMouse
- IsotypeIgG
- Scientific DescriptionRegulates cell cycle checkpoints and apoptosis in response to DNA damage, particularly to DNA double-strand breaks. Inhibits CDC25C phosphatase by phosphorylation on Ser-216, preventing the entry into mitosis. May also play a role in meiosis. Regulates the TP53 tumor suppressor through phosphorylation at Thr-18 and Ser-20.
- ReactivityCanine, Human, Monkey, Mouse, Rat
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203