Cisplatin modified DNA antibody [CP9/19]
GTX17412
ApplicationsDot Blot, ImmunoFluorescence, ImmunoPrecipitation, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityMouse
Overview
- SupplierGeneTex
- Product NameCisplatin modified DNA antibody [CP9/19]
- Delivery Days Customer10
- ApplicationsDot Blot, ImmunoFluorescence, ImmunoPrecipitation, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDCP9/19
- HostRat
- IsotypeIgG
- Scientific DescriptionThis antibody enables the quantification of cisplatin-induced adducts on DNA. This antibody has also been recently used for isolation of DNA fragments carrying adducts to enhance the sensitivity of subsequent PCR-based analyses and is central to ongoing studies of variation in the nature of cisplatin adducts formed in different cell lines.
- ReactivityMouse
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Metformin inhibits metastatic breast cancer progression and improves chemosensitivity by inducing vessel normalization via PDGF-B downregulation. Wang JC et al., 2019 Jun 4, J Exp Clin Cancer ResRead more
- Transient activation of tumoral DNA damage tolerance pathway coupled with immune checkpoint blockade exerts durable tumor regression in mouse melanoma. Zhuo M et al., 2021 May, Pigment Cell Melanoma ResRead more