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ProductsBack/Clathrin heavy chain antibody [X22] - KO/KD Validated
GTX22731 IHC-P Image
GTX22731 IHC-P Image
GTX22731 IHC-P Image

Clathrin heavy chain antibody [X22] - KO/KD Validated

Research Use Only
GTX22731
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking, Other Application
DownloadDatasheet
Product group Antibodies
ReactivityBovine, Canine, Hamster, Human, Mouse, Primate, Rat
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Overview

  • Supplier
    GeneTex
  • Product Name
    Clathrin heavy chain antibody [X22] - KO/KD Validated
  • Delivery Days Customer
    10
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking, Other Application
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    X22
  • Concentration
    6 mg/ml
  • Host
    Mouse
  • Isotype
    IgG
  • Scientific Description
    Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains. [provided by RefSeq, Jul 2008]
  • Reactivity
    Bovine, Canine, Hamster, Human, Mouse, Primate, Rat
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Cell surface epidermal growth factor receptors increase Src and c-Cbl activity and receptor ubiquitylation. Parks EE et al., 2014 Sep 12, J Biol Chem
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  • Convallatoxin enhance the ligand-induced mu-opioid receptor endocytosis and attenuate morphine antinociceptive tolerance in mice. Chao PK et al., 2019 Feb 20, Sci Rep
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  • Phosphorylation of protease-activated receptor-2 differentially regulates desensitization and internalization. Ricks TK et al., 2009 Dec 4, J Biol Chem
    Read more
  • Protease-activated Receptor-4 Signaling and Trafficking Is Regulated by the Clathrin Adaptor Protein Complex-2 Independent of beta-Arrestins. Smith TH et al., 2016 Aug 26, J Biol Chem
    Read more
  • Size-dependent toxicity and cell interaction mechanisms of gold nanoparticles on mouse fibroblasts. Coradeghini R et al., 2013 Mar 13, Toxicol Lett
    Read more