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ProductsBack/Cofilin 1 (phospho Ser3) antibody - Orthogonal Validated
GTX50199 ICC/IF Image
GTX50199 ICC/IF Image
GTX50199 ICC/IF Image

Cofilin 1 (phospho Ser3) antibody - Orthogonal Validated

Research Use Only
GTX50199
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
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Product group Antibodies
ReactivityHuman, Mouse, Rat
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Overview

  • Supplier
    GeneTex
  • Product Name
    Cofilin 1 (phospho Ser3) antibody - Orthogonal Validated
  • Delivery Days Customer
    10
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Host
    Rabbit
  • Isotype
    IgG
  • Modification Type
    Phosphorylated
  • Scientific Description
    The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • PLD2 regulates microtubule stability and spindle migration in mouse oocytes during meiotic division. Liu X et al., 2017, PeerJ
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