Connexin 32 Antibody / GJB1
ORB386047
Overview
- SupplierBiorbyt
- Product NameConnexin 32 Antibody / GJB1
- Delivery Days Customer16
- ApplicationsFlow Cytometry
- Applications SupplierImmunofluorescence: 1-2ug/ml,Flow cytometry: 0.5-1ug/million cells,Western blot: 0.5-1ug/ml,Immunohistochemistry (Frozen): 0.5-1ug/ml for 30 min at RT FACS, IF, IHC-Fr, WB
- CertificationResearch Use Only
- Clone IDM12.13
- IsotypeIgG
- Scientific DescriptionThis Ab recognizes a protein of 27-32kDa, identified as Connexin 32. The connexin family of proteins forms hexameric complexes called connexons that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane a-helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences arise from specific amino-acid substitutions in the most highly conserved domains, the transmembrane and extracellular regions. Each of the approximately 20-connexin isoforms produces channels with distinct permeability and electrical and chemical sensitivities; therefore, one connexin usually cannot fully substitute for another.
- UNSPSC12352203