Copper Transporting ATPase 2 antibody, MAb (RPE)
ORB149815
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
Overview
- SupplierBiorbyt
- Product NameCopper Transporting ATPase 2 antibody, MAb (RPE)
- Delivery Days Customer10
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
- Applications SupplierWB (1:1000), ICC/IF (1:100) ICC, IP, WB, IHC
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDS62-29
- Concentration1 mg/ml
- ConjugateRPE
- HostMouse
- IsotypeIgG1
- Scientific DescriptionMouse monoclonal to Copper Transporting ATPase 2 (RPE). The copper efflux transporters ATP7A and ATP7B sequester intracellular copper into the vesicular secretory pathway for export from the cell. ATP7b is an important protein for copper transport and elimination of excess copper from the body. ATP7b transports metals in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene; A is found in the liver, kidney, and brain, the shorter form B is found in brain tissue, and the third isoform, known as WND/140 KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilsons disease, an inherited disorder causing copper poisoning in the brain and liver, characterized by neurological symptoms and hepatic damage..
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C
- UNSPSC12352203