Overview
- SupplierGeneTex
- Product NameCOX4 antibody [GT6310]
- Delivery Days Customer9
- CertificationResearch Use Only
- Clone IDGT6310
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionCytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3 of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Ca2+ influx-mediated dilation of the endoplasmic reticulum and c-FLIPL downregulation trigger CDDO-Me-induced apoptosis in breast cancer cells. Jeong SA et al., 2015 Aug 28, OncotargetRead more
- Lead (Pb) induced ATM-dependent mitophagy via PINK1/Parkin pathway. Gu X et al., 2018 Jul, Toxicol LettRead more
- NIX compensates lost role of parkin in cd-induced mitophagy in HeLa cells through phosphorylation. Naeem S et al., 2020 Jun 15, Toxicol LettRead more