Bio-Connect
GTX628886 WB Image
GTX628886 WB Image
GTX628886 WB Image

COX4 antibody [GT6310]

Research Use Only
GTX628886
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    COX4 antibody [GT6310]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Clone ID
    GT6310
  • Concentration
    1 mg/ml
  • Isotype
    IgG
  • Scientific Description
    Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3 of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Ca2+ influx-mediated dilation of the endoplasmic reticulum and c-FLIPL downregulation trigger CDDO-Me-induced apoptosis in breast cancer cells. Jeong SA et al., 2015 Aug 28, Oncotarget
    Read more
  • Lead (Pb) induced ATM-dependent mitophagy via PINK1/Parkin pathway. Gu X et al., 2018 Jul, Toxicol Lett
    Read more
  • NIX compensates lost role of parkin in cd-induced mitophagy in HeLa cells through phosphorylation. Naeem S et al., 2020 Jun 15, Toxicol Lett
    Read more