Bio-Connect
GTX114330 IHC-P Image
GTX114330 IHC-P Image
GTX114330 IHC-P Image

COX4 antibody

Research Use Only
GTX114330
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    COX4 antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.42 mg/ml
  • Isotype
    IgG
  • Scientific Description
    Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3 of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

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  • An Artificial Reaction Promoter Modulates Mitochondrial Functions via Chemically Promoting Protein Acetylation. Shindo Y et al., 2016 Jul 4, Sci Rep
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  • Cardiac-specific microRNA-125b deficiency induces perinatal death and cardiac hypertrophy. Chen CY et al., 2021 Jan 27, Sci Rep
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  • Characterization of human AlkB homolog 1 produced in mammalian cells and demonstration of mitochondrial dysfunction in ALKBH1-deficient cells. Mueller TA et al., 2018 Jan 1, Biochem Biophys Res Commun
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  • Inhibition of Avian Influenza A Virus Replication in Human Cells by Host Restriction Factor TUFM Is Correlated with Autophagy. Kuo SM et al., 2017 Jun 13, MBio
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  • Insulin in combination with selenium inhibits HG/Pal-induced cardiomyocyte apoptosis by Cbl-b regulating p38MAPK/CBP/Ku70 pathway. Xu TJ et al., 2016 Jul, Eur Rev Med Pharmacol Sci
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  • Knockout Serum Replacement Promotes Cell Survival by Preventing BIM from Inducing Mitochondrial Cytochrome C Release. Ishii Y et al., 2015, PLoS One
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  • Metformin triggers the intrinsic apoptotic response in human AGS gastric adenocarcinoma cells by activating AMPK and suppressing mTOR/AKT signaling. Lu CC et al., 2019 Apr, Int J Oncol
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  • Mitochondrial proteomics with siRNA knockdown to reveal ACAT1 and MDH2 in the development of doxorubicin-resistant uterine cancer. Lo YW et al., 2015 Apr, J Cell Mol Med
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