CREB antibody

GeneTex

CREB antibody

10

Gel Shift Assay, Western Blot, ELISA

Research Use Only

Polyclonal

2.56 mg/ml

Rabbit

IgG

cyclic AMP responsive element binding protein (CREB) is a ubiquitous transcription factor regulated by changes in cyclic AMP (cAMP) levels. CREB binds as a homodimer to CRE sites (cAMP response elements) and belongs to the basic leucine zipper family of DNA binding proteins. Increases in cAMP levels result in the specific phosphorylation of CREB by protein kinase A. Phosphorylated CREB interacts with the transcriptional co-activator CBP (CREB binding protein or p265). It has recently been demonstrated that CREB phosphorylation correlates with light regulated circadian rhythms.

Human, Mouse, Rat

2°C to 8°C,-20°C

12352203