GTX103005 WB Image
GTX103005 WB Image
CSE1L antibody
GTX103005
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameCSE1L antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.4 mg/ml
- IsotypeIgG
- Scientific DescriptionProteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- A pharmacological probe identifies cystathionine beta-synthase as a new negative regulator for ferroptosis. Wang L et al., 2018 Sep 26, Cell Death DisRead more
- Ets-1 facilitates nuclear entry of NFAT proteins and their recruitment to the IL-2 promoter. Tsao HW et al., 2013 Sep 24, Proc Natl Acad Sci U S ARead more