Bio-Connect

CUL4A antibody, PAb

Research Use Only
ORB66954
Biorbyt
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biorbyt
  • Product Name
    CUL4A antibody, PAb
  • Delivery Days Customer
    16
  • Applications
    Western Blot
  • Applications Supplier
    WB:1:1000-1:5000 WB
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Rabbit polyclonal to CUL4A.CUL4A is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNAdamage-response proteins. CUL4A is a core component of multiple cullin-RING-based E3 ubiquitinproteinligase complexes which mediate the ubiquitination and subsequent proteasomal degradationof target proteins. As a scaffold protein, CUL4A may contribute to catalysis through positioning of thesubstrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complexis dependent on the neddylation of the cullin subunit. CUL4A may be involved in ubiquitination of JUN,P53, CDKN1B and HOXA9.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203