CXCL10 / IP10 antibody
GTX10378
Overview
- SupplierGeneTex
- Product NameCXCL10 / IP10 antibody
- Delivery Days Customer10
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- HostGoat
- IsotypeIgG
- Scientific DescriptionIP-10 is a member of the C-X-C, or alpha chemokine class. It does not contains the ELR domain immediately preceding the first cysteine residue near the amino terminus. Other chemokines in this group include mouse CRG, Mig, PBSF/SDF-1, and PF4. These chemokines act primarily as chemoattractants and activate monocytes, dendritic cells, T lymphocytes, natural killer cells, B lymphocytes, basophils, and eosinophils. IP-10 was originally identified as an IFN-gamma- inducible gene in monocytes, fibroblasts, and endothelial cells. IP-10 is a chemoattractant for activated T lymphocytes. It is a potent inhibitor of angiogenesis and displays a thymus-dependent antitumor effect. IP-10 is an approximately 8.7 kDa polypeptide of 78 amino acids. The precursor form of human IP-10 consists of 98 amino acids. To generate the mature IP-10, the precursor cleaves its 21 amino acid signal peptide. Human IP-10 shows 67% amino acid homology to mouse CRG-2.
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203