Overview
- SupplierGeneTex
- Product NameCXCR7 antibody [C1C2], Internal
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Activation of MAPK Signaling by CXCR7 Leads to Enzalutamide Resistance in Prostate Cancer. Li S et al., 2019 May 15, Cancer ResRead more
- Atypical chemokine receptor ACKR3/CXCR7 controls postnatal vasculogenesis and arterial specification by mesenchymal stem cells via Notch signaling. Wei ST et al., 2020 May 4, Cell Death DisRead more
- Chemokine receptor CXCR7 is a functional receptor for CXCL12 in brain endothelial cells. Liu Y et al., 2014, PLoS OneRead more
- CX Chemokine Receptor 7 Contributes to Survival of KRAS-Mutant Non-Small Cell Lung Cancer upon Loss of Epidermal Growth Factor Receptor. Liu B et al., 2019 Mar 30, Cancers (Basel)Read more
- CXCR4/CXCR7/CXCL12 axis promotes an invasive phenotype in medullary thyroid carcinoma. Werner TA et al., 2017 Dec 5, Br J CancerRead more
- CXCR7 maintains osteosarcoma invasion after CXCR4 suppression in bone marrow microenvironment. Han Y et al., 2017 May, Tumour BiolRead more
- CXCR7 promotes melanoma tumorigenesis via Src kinase signaling. Xu S et al., 2019 Feb 25, Cell Death DisRead more
- CXCR7 Reactivates ERK Signaling to Promote Resistance to EGFR Kinase Inhibitors in NSCLC. Becker JH et al., 2019 Sep 1, Cancer ResRead more
- CXCR7 regulates epileptic seizures by controlling the synaptic activity of hippocampal granule cells. Xu T et al., 2019 Oct 31, Cell Death DisRead more
- D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling. Song S et al., 2021 Jun, EBioMedicineRead more