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GTX100027 WB Image
GTX100027 WB Image
GTX100027 WB Image

CXCR7 antibody [C1C2], Internal

Research Use Only
GTX100027
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    CXCR7 antibody [C1C2], Internal
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Activation of MAPK Signaling by CXCR7 Leads to Enzalutamide Resistance in Prostate Cancer. Li S et al., 2019 May 15, Cancer Res
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  • Atypical chemokine receptor ACKR3/CXCR7 controls postnatal vasculogenesis and arterial specification by mesenchymal stem cells via Notch signaling. Wei ST et al., 2020 May 4, Cell Death Dis
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  • Chemokine receptor CXCR7 is a functional receptor for CXCL12 in brain endothelial cells. Liu Y et al., 2014, PLoS One
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  • CX Chemokine Receptor 7 Contributes to Survival of KRAS-Mutant Non-Small Cell Lung Cancer upon Loss of Epidermal Growth Factor Receptor. Liu B et al., 2019 Mar 30, Cancers (Basel)
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  • CXCR4/CXCR7/CXCL12 axis promotes an invasive phenotype in medullary thyroid carcinoma. Werner TA et al., 2017 Dec 5, Br J Cancer
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  • CXCR7 maintains osteosarcoma invasion after CXCR4 suppression in bone marrow microenvironment. Han Y et al., 2017 May, Tumour Biol
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  • CXCR7 promotes melanoma tumorigenesis via Src kinase signaling. Xu S et al., 2019 Feb 25, Cell Death Dis
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  • CXCR7 Reactivates ERK Signaling to Promote Resistance to EGFR Kinase Inhibitors in NSCLC. Becker JH et al., 2019 Sep 1, Cancer Res
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  • CXCR7 regulates epileptic seizures by controlling the synaptic activity of hippocampal granule cells. Xu T et al., 2019 Oct 31, Cell Death Dis
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  • D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling. Song S et al., 2021 Jun, EBioMedicine
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