GTX113670 WB Image
CYP17A1 antibody [N3C2], Internal
GTX113670
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameCYP17A1 antibody [N3C2], Internal
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.81 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Assessment of the potential of polyphenols as a CYP17 inhibitor free of adverse corticosteroid elevation. Lin CJ et al., 2014 Aug 1, Biochem PharmacolRead more