GTX104424 WB Image
GTX104424 WB Image
CYP1B1 antibody
GTX104424
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameCYP1B1 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.63 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- 2-Methoxyestradiol, an endogenous 17beta-estradiol metabolite, inhibits microglial proliferation and activation via an estrogen receptor-independent mechanism. Schaufelberger SA et al., 2016 Mar 1, Am J Physiol Endocrinol MetabRead more
- Target disruption of ribosomal protein pNO40 accelerates aging and impairs osteogenic differentiation of mesenchymal stem cells. Lin YM et al., 2016 Jan 22, Biochem Biophys Res CommunRead more