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GTX113219 IHC-P Image
GTX113219 IHC-P Image
GTX113219 IHC-P Image

Cytokeratin 5 antibody

Research Use Only
GTX113219
GeneTex
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Product group Antibodies
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Overview

  • Supplier
    GeneTex
  • Product Name
    Cytokeratin 5 antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.35 mg/ml
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Filaggrin silencing by shRNA directly impairs the skin barrier function of normal human epidermal keratinocytes and then induces an immune response. Dang NN et al., 2015 Jan, Braz J Med Biol Res
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  • Knockdown of filaggrin influences the epidermal terminal differentiation via MAPK pathway in normal human epidermal keratinocytes. Dang N et al., 2015 Feb, Mol Biol Rep
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  • Knock-down of filaggrin influences the mitogen-activated protein kinases signaling pathway in normal human epidermal keratinocytes. Wang S et al., 2018 Oct, Med Sci (Paris)
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  • LncRNA expression profile of deltaNp63alpha in cervical squamous cancers and its suppressive effects on LIF expression. Qian L et al., 2017 Aug, Cytokine
    Read more
  • MAOA-a novel decision maker of apoptosis and autophagy in hormone refractory neuroendocrine prostate cancer cells. Lin YC et al., 2017 Apr 12, Sci Rep
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  • MAPK Pathway Involved in Epidermal Terminal Differentiation of Normal Human Epidermal Keratinocytes. Meng X et al., 2018, Open Med (Wars)
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  • Retinoic acid receptor gamma activation promotes differentiation of human induced pluripotent stem cells into esophageal epithelium. Koterazawa Y et al., 2020 Aug, J Gastroenterol
    Read more