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D type cyclin antibody [94B]

Research Use Only
GTX12208
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    D type cyclin antibody [94B]
  • Delivery Days Customer
    10
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    94B
  • Concentration
    1 mg/ml
  • Host
    Rat
  • Isotype
    IgG
  • Scientific Description
    This protein was identified by the interaction with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Two alternatively spliced variants, which encode distinct isoforms, have been reported.
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203