Overview
- SupplierGeneTex
- Product NameDHFR antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1.54 mg/ml
- IsotypeIgG
- Scientific DescriptionDihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- High pemetrexed sensitivity of docetaxel-resistant A549 cells is mediated by TP53 status and downregulated thymidylate synthase. Kuo WT et al., 2017 Nov, Oncol RepRead more
- The ERK-ZEB1 pathway mediates epithelial-mesenchymal transition in pemetrexed resistant lung cancer cells with suppression by vinca alkaloids. Chiu LY et al., 2017 Jan 12, OncogeneRead more