DNMT1 antibody, MAb (ATTO-488)

Biorbyt

DNMT1 antibody, MAb (ATTO-488)

10

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

WB (1:1000), ICC/IF (1:100) ICC, WB

Research Use Only

Monoclonal

1C4-1A6

1 mg/ml

Atto 488

Mouse

IgG1

Mouse monoclonal to DNMT1 (ATTO-488). Hsp47 is a chaperone protein, member of the superfamily of serine proteinase inhibitors. Also known as SERPINH1, a serine proteinase inhibitor. It is a stress protein that resides in the endoplasmic reticulum, has an active role on the intracellular process of folding, assembly and secretion of pro-collagens. Recent studies have shown the association of on an increased expression of Hsp47 around fibrotic lesions. The identification of a novel biomarker on cell therapies aimed to reduce the progression of fibrotic diseases, could be used potentially as a universal marker, since Hsp47 binds a single substrate. Type I collagen is fundamental during the healing process after a myocardial infarction. It is critical in the position of collagen-produced cells and the assembly of collagen fibrils..

Human

2°C to 8°C

12352203