DNMT1 antibody, PAb
ORB66726
Overview
- SupplierBiorbyt
- Product NameDNMT1 antibody, PAb
- Delivery Days Customer16
- ApplicationsWestern Blot
- Applications SupplierWB:1:1000-1:5000 WB
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- HostRabbit
- IsotypeIgG
- Scientific DescriptionRabbit polyclonal to DNMT1.DNA (cytosine-5)-methyltransferase 1 (DNMT1) plays a role in methylating CpG residues.Preferentially methylates hemimethylated DNA and regulates tissue-specific patterns of methylatedcytosine residues. During S phase of the cell cycle DNMT1 localizes at replication sites conservingmethylation patterns in the newly synthesized strand, maintaining epigenetic inheritance. During G2and M phases of the cell cycle, DNMT1 associates with chromatin maintaining DNA methylationirrespective of replication. Atypical DNA methylation patterns have been shown to be associated withcertain human tumors and developmental abnormalities.
- ReactivityHuman, Mouse
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203