DR5 antibody [10B4]

GeneTex

DR5 antibody [10B4]

10

Other Application

Research Use Only

Monoclonal

10B4

500 ug/ml

Mouse

IgG

The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]

Human

2°C to 8°C,-20°C

12352203