Overview
- SupplierGeneTex
- Product NameDYNC1LI1 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionActs as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Gene targets of mouse miR-709: regulation of distinct pools. Surendran S et al., 2016 Jan 8, Sci RepRead more
- POPX2 phosphatase regulates cell polarity and centrosome placement. Hoon JL et al., 2014, Cell CycleRead more
- Resources for the Comprehensive Discovery of Functional RNA Elements. Sundararaman B et al., 2016 Mar 17, Mol CellRead more
- Targeting long noncoding RNA PMIF facilitates osteoprogenitor cells migrating to bone formation surface to promote bone formation during aging. Li D et al., 2021, TheranosticsRead more
- The mitotic tensegrity guardian tau protects mammary epithelia from katanin-like1-induced aneuploidy. Sudo H et al., 2016 Aug 16, OncotargetRead more